解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Bile salts have been shown to act on lipoprotein-X (LP-X) in vitro to induce a false-negative electrophoretic test. The aim of the present study was to investigate the relationship between serum LP-X and serum bile acids in patients with cholestasis. The in vitro concentration of bile salts required to induce a negati...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000198402
更新日期:1979-01-01 00:00:00
abstract::Amylase/creatinine clearance ratio (CAm/CCr), urinary protein concentration and urinary protein pattern were studied in 102 samples from 27 patients with acute pancreatitis and in 46 controls. Raised CAm/CCr, proteinuria and a tubular protein pattern were present in 74, 56 and 96% of the patients, respectively. Howeve...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000198397
更新日期:1979-01-01 00:00:00
abstract::Isolated acinar cells from rat pancreas responded well to hormonal treatment. Both secretin (synthetic and highly purified from porcine origin) and CCK-octapeptide stimulated amylase secretion in these cells. The response in both cases was very rapid. A maximal output of enzyme was reached within 5-10 min after the ad...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000198316
更新日期:1979-01-01 00:00:00
abstract::D-Galactosamine administration to rats (400 mg/kg) by intraperitoneal injection induced biochemical alterations in liver plasma membranes. Alterations were studied 4, 16 and 24 h after D-galactosamine injection. Plasma membrane 5'-mononucleotidase activity decreased to 40% of control values. Carbohydrate composition w...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000198373
更新日期:1979-01-01 00:00:00
abstract::Carbonic anhydrase (CA) was found to be equally susceptible to direct inhibition by ethanol, whether the enzyme originated from homogenates of rabbit gastric, duodenal, or ileal mucosa. When gastric mucosa was separated into a soluble (cytoplasmic) and a membrane fraction, the membrane CA was more susceptible to ethan...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000198130
更新日期:1978-07-01 00:00:00
abstract::Intestinal absorption after extensive small bowel resections, for diseases other than Crohn's disease, was studied in 17 patients. When the ileocecal valve and the right colon were preserved, malabsorption was transient and moderate and had no prejudicial nutritional effect (fecal fat: 8.8 +/- 1.8 g/24 h in resections...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000198220
更新日期:1978-01-01 00:00:00
abstract::Lecithin: cholesterol acyltransferase activity has been measured in serum from patients with various liver disorders and positive LP-X tests and from healthy subjects. Statistical analysis indicated that lecithin: cholesterol acyltransferase activity provided no help in the discrimination between the persons of both g...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000198149
更新日期:1978-01-01 00:00:00
abstract::L-Amino acid solution given intravenously in Heidenhain pouch dogs resulted in marked changes of both basal and pentagastrin-stimulated gastric secretions. During a 1-hour amino acid infusion, a significant augmentation of pentagastrin-induced secretion was observed. A significant increase of secretion during amino ac...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000198207
更新日期:1978-01-01 00:00:00
abstract::An improved GLC method was employed to study individual serum bile acids in 14 control subjects after a 12-hour fast followed by a standard fatty meal. Peripheral venous blood samples were obtained at 15-min intervals for up to 2 h in 7 subjects, and 4 h in 2 subjects. The fasting total bile acids, and cholic:chenodeo...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000198094
更新日期:1978-01-01 00:00:00
abstract::Serum antibodies directed against 5 alimentary antigens and antigen-antibody complexes were determined in 15 control subjects and in 15 patients with alcoholic liver cirrhosis. Cirrhotic patients presented an increased immune response against these antigens. Antigen-antibody complexes were detected in the fasting plas...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000198162
更新日期:1978-01-01 00:00:00
abstract::The form in which copper is bound in bile was studied in bile from patients with Wilson's disease, control subjects and rats. Bile was labelled with 64Cu. Sephadex column chromatography using gels G-200--G-10 showed a major 64Cu and protein peak of about 5,000 daltons and a minor peak of about 8,000 daltons. A high-mo...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000198027
更新日期:1977-01-01 00:00:00
abstract::Human gastric mucosal adenylate cyclase has been shown to be sensitive to histamine and catecholamines. Stimulation of enzyme activity by histamine and catecholamines were selectively blocked by cimetidine and propranolol, respectively. Combination of both hormones at maximally effective concentrations were additive, ...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000198069
更新日期:1977-01-01 00:00:00
abstract::The ratio of 6beta-hydroxycortisol to 17-hydroxycorticosteroids in the urine of 73 patients with liver disease, and 53 controls has been measured. The mean ratio was significantly greater in the liver disease group (p less than 0.001), this elevation being most marked among patients with liver metastases and patients ...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000198068
更新日期:1977-01-01 00:00:00
abstract::The effect of maximal doses of cholecystokinin and caerulein on lipase and chymotropsin concentrations were compared in large groups of patients with almost equal capacities of bicarbonate secretion. The responsiveness of the pancreas is, as a whole, higher with caerulein than with cholecystokinin, this feature being ...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000197987
更新日期:1977-01-01 00:00:00
abstract::Zinc nutriture has been studies in 30 patients with Crohn's disease using plasma zinc, hair zinc, and taste acuity as indices. Significant reductions in plasma zinc concentrations and taste acuity were seen in the patient groups as compared with normal controls. Hair zinc content was also generally low with several de...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000198059
更新日期:1977-01-01 00:00:00
abstract::108 adult patients and 34 children with chronic active hepatitis (CAH) are divided in four groups on the basis of presence and absence of hepatitis B surface antigen (HBsAg) and autoantibodies (AutoAb). There are significant differences in the numeric distribution among the four groups and the sex distribution between...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000198011
更新日期:1977-01-01 00:00:00
abstract::Fundic mucosal extracts of the cat were examined by chromatography using DEAE-cellulose at pH 5.3. The peaks of proteolytic activity located by this method were shown to be heterogeneous on electrophoresis. By electrophoresis of individual homogenous chromatographic fractions 9 separate zones of proteolytic activity w...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000197919
更新日期:1976-01-01 00:00:00
abstract::Electrophoretic studies of inactive ductal pancreatic secretions, collected on five successive days following operation, demonstrated up to 18 protein bands. Comparison of the densitometric scans on the first and fourth days was as follows: the patterns from different individuals appeared similar during the periods of...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000197936
更新日期:1976-01-01 00:00:00
abstract::A method of obtaining linear plots of protein-flow data from human pancreatic ductal secretions is described. The protein concentration in pancreatic secretions, when related to flow rates in two individuals, gave similar regression lines, with the correlation coefficients or r = -0.97 and -0.98, respectively, and slo...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000197922
更新日期:1976-01-01 00:00:00
abstract::Buffalo strain male and female rats were given methylazoxymethanol acetate (20% solution) intraperitoneally 20 mg/kg body weight weekly for 9 weeks, and killed 27 weeks later. Carcinomas of the large intestine, predominantly in the descending colon, developed in some of the rats. The incidence was higher in male than ...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000197946
更新日期:1976-01-01 00:00:00
abstract::Outpatient treatment of haemorrhoids by elastic band ligation without anaesthetic was performed in 75 patients. Clinical review showed that 65 returned to work within 24 h of ligation, 8 in 48 h and 2 after 48 h. No patient required hospitalisation for either rectal bleeding or pain after ligation. In the first week a...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000197658
更新日期:1975-01-01 00:00:00
abstract::Repeated intravenous injections of 2.0 clinical units (CU) secretin per kg body weight showed no effect on jejunal glucose absorption and net water movement in perfusion studies in vivo. The in vitro uptake of galactose and 3-O-methylglucose was not altered by a secretin load given 12 min before sacrifice. The values ...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000197730
更新日期:1975-01-01 00:00:00
abstract::Natural motilin was investigated for its effect on gastrointestinal motor activity in anesthetized dogs. In doses starting from 10 ng/kg as single injection and 100 ng/kg-h as intravenous infusion, motilin induced phasic pressure changes in the lower esophageal sphincter (LES) and in the lumen of the fundus, antrum, a...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000197714
更新日期:1975-01-01 00:00:00
abstract::Electroencephalographic tracings of 50 patients with ulcerative colitis (UC) were compared with those of 75 controls. In the UC patients a 24% incidence of abnormal tracings was found as compared with an 8% incidence in the controls. A higher incidence of abnormal electroencephalograms was found among active cases of ...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000197695
更新日期:1975-01-01 00:00:00
abstract::The isoenzymatic pattern of aldolase was determined by immunoprecipitation with specific anti-aldolase A, B and C sera in 21 pathological liver tissues and in the sera of normals (n equals 20), liver cirrhotics (n equals 52) and hepatoma patients (n equals 22). The increase of aldolase A in primary liver cell carcinom...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000197663
更新日期:1975-01-01 00:00:00
abstract::Since biguanides are known to inhibit hexose and amino acid absorption in vivo and in vitro as well as vitamin B12 absorption the effect of phenethylbiguanide on taurocholate (TC) and water absorption was measured in rat ileum in vivo. Phenethylbiguanide exhibited a time-dependent inhibitory effect on TC- and water ab...
journal_title:Digestion
pub_type: 杂志文章
doi:10.1159/000197672
更新日期:1975-01-01 00:00:00